SANTA CLARA, Calif. (AP) — The reeling San Francisco 49ers defense already had plenty to be concerned with this week before the added distraction of Aldon Smith's arrest.
First and foremost: Quarterback Andrew Luck, running back Trent Richardson and the new-look offense of the Indianapolis Colts.
The 49ers look to rebound from last week's tough loss in Seattle with a banged-up lineup.
San Francisco will be breaking in a new starting nose tackle against the Colts, has yet to gain clearance for starting rookie safety Eric Reid and has three other key starters who either missed practice or were limited this week with injuries.
However, a defense that ranked third in the NFL last season is accustomed to the adversity and welcomes the challenge of a Colts backfield strengthened earlier this week when the team acquired Richardson from the Browns.
Smith was arrested Friday morning in San Jose on suspicion of DUI and marijuana possession, but it was business as usual for San Francisco's defense as Smith practiced with the team later in the afternoon. Smith has been limited in practice all week due to a back injury.
Coach Jim Harbaugh said he expects Smith — second in the NFL with 3½ sacks — to play Sunday, and the 49ers (1-1) appeared to be keeping their focus on bouncing back against the Colts after being routed 29-3 in Seattle.
"I don't think it's a distraction," cornerback Carlos Rogers said Friday. "I think this team is strong. We're still salty about last week's loss instead of worrying about any problems that come up. We've got Indy, and that's our main focus. Everybody has to handle adversity when there's something wrong. If you have a hole in your roof, you patch it up."
The 49ers are patching a hole in their defensive front created when starting nose tackle Ian Williams was lost for the season after breaking his left ankle against Seattle. He'll be replaced by Glenn Dorsey, who may be San Francisco's healthiest lineman Sunday. Tackles Ray McDonald (injuries to both ankles) and Justin Smith (shoulder) both missed practice this week and McDonald was listed Friday as questionable to play against the Colts.
Also questionable is Reid, who left last week's game in the second quarter after sustaining a concussion. Reid said he has passed all tests according to the NFL protocol for concussions and expects to return against the Colts. He still needs to pass a contact test before he can be cleared.
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