Here's a look at each game in the series' history:
Oct. 27, 2012
Notre Dame 30, Oklahoma 13
Gaylord Family-Oklahoma Memorial Stadium
The game: Oklahoma battled back to tie it 13-13 early in the fourth quarter, but the Irish dominated from that point on. Manti Te'o's interception with less than five minutes remaining all but put the game out of reach as Notre Dame kept its national title hopes alive while the Sooners dropped their second home game of the season.
Star: Manti Te'o, Notre Dame. The interception was the signature (on-the-field) moment in Te'o's season, helping boost him to a second-place finish in Heisman Trophy-voting. Te'o finished with 11 tackles.
Quotable: “It stinks to lose. But in the end, let's recognize we played an excellent football team. I'm not looking through any rose-colored glasses, looking to get any moral victories.” — Bob Stoops, Sooners coach
Oct. 2, 1999
Notre Dame 34, Oklahoma 30
Notre Dame Stadium
The game: After starting 3-0, OU lost for the first time in the Bob Stoops era as the Sooners let a 30-14 lead early in the fourth quarter evaporate as Notre Dame snapped a three-game losing streak. The Irish took the lead on a 98-yard, 11-play drive in the fourth quarter where they completed just two passes. Notre Dame ran for 284 yards.
Star: Jarious Jackson, Notre Dame. The Irish quarterback ran for 107 yards and threw for 276 in leading the comeback.
Quotable: “To be on the road like that, to play a team with that type of tradition, that type of history, to be in the position to win and have it but then lose it right at the last minute, it was a horrible feeling. That was one of those games that we looked at as a defining moment for what we were trying to do. … Hindsight, you look back on it and you realize what a defining moment that was, because it was really teaching us how to control our emotions and how to play in the moment on the road in big games.” — Josh Norman, Sooners reciever
Sept. 21, 1968
Notre Dame 45, Oklahoma 21
Notre Dame Stadium
The game: Notre Dame took a 21-14 lead just before the half on Terry Hanratty's touchdown pass to Jim Seymour with less than a minute remaining. The Fighting Irish dominated the second half, mostly on the ground. Notre Dame wound up with 571 yards of total offense, 357 on the ground.
Star: Jim Seymour, Notre Dame. Seymour became the Fighting Irish's all-time leading receiver with more than 100 receiving yards and a pair of touchdown catches.
Quotable: “No, I don't believe we would have blown the game open. There were no psychological ups and downs for us. This wasn't the reason we got beat today. We got beat because Notre Dame has a much better football team than we have.” — Chuck Fairbanks, Sooners coach on OU leading 14-7 and threatening to score early. The Sooners wound up missing a field goal on the drive.
Oct. 22, 1966
Notre Dame 38, Oklahoma 0
The game: After a scoreless first quarter, Notre Dame dominated the middle two, scoring 38 points in a 23:08 span, scoring on six of seven drives in the second and third quarters to give the Sooners their worst loss since a 47-0 setback to Oklahoma State in 1945.
Star: Alan Page, Notre Dame. Page, a future member of both the College Football and Pro Football halls of fame and a current justice on the Minnesota Supreme Court, was the key disruptive force to the Notre Dame defense that shut the Sooners out.
Quotable: “I think losing 7-0 would've been worse. If you're gonna get beat, get beat bad. If it'd been close, it'd been because of an official's call, a coach's bonehead mistake, a player's error or something like that.” — Jim Mackenzie, Sooners coach.
Sept. 29, 1962
Notre Dame 13, Oklahoma 7
The game: Oklahoma drove 71 yards to the 1 late in the game but could not finish the drive off as the Irish defense held the Sooners on four consecutive plays inside the 5.
Star: Daryle Lamonica, Notre Dame. The Irish quarterback completed all five of his passes, rushed for 25 yards and had an interception shortly after fumbling the ball away on offense to help the Irish escape Norman with a win.
Quotable: “When you don't score with a first down within the five there's something very wrong with your procedure. … We didn't execute well at all on the goal line. But at the same time you've got to give the opposition credit for executing very well. But that doesn't mitigate anything or soothe how you feel. I think you ought to be able to score. When you don't, you have failed to execute within the percentages that normally go with you in that situation.” — Bud Wilkinson, Sooners coach.
Sept. 30, 1961
Notre Dame 19, Oklahoma 6
Notre Dame Stadium
The game: Mike Lind scored a pair of touchdowns, the last midway through the fourth quarter, to help Notre Dame start the season with a win. The Sooners had the chance to take the lead early, but Bill Van Burkleo's potential touchdown pass to Mike McClellan sailed high and the Irish blocked the subsequent field goal try. The Sooners wound up dropping five consecutive games to start the season.
Star: Angelo Dabiero, Notre Dame. Dabiero started the scoring with a 51-yard touchdown run, set up two more scores with long runs and finished with 176 yards on just 11 carries. Dabiero topped Oklahoma's rushing total by more than 50 yards.
Quotable: “We have to do our share. We fell to pieces. I sure hope we can come back. We all have to get together.” — Leon Cross, Sooners guard, on the play of the second team.
Nov. 16, 1957
Notre Dame 7, Oklahoma 0
The game: The most celebrated game in the series. Notre Dame snapped Oklahoma's 47-game winning streak with a fourth-quarter three-yard touchdown run by Dick Lynch. The Sooners defense had a pair of earlier goal-line stands in the game. Oklahoma had a late chance to tie it, but Bennett Watts' pass was intercepted by John Pellow, sealing the Irish win. The Sooners managed just 145 yards of offense.
Star: Nick Pietrosante, Notre Dame. The fullback ran for more than 50 yards, and Notre Dame totaled 169 yards on the ground.
Quotable: “I don't think any of us believed it. You looked up in the stands and people were waiting for the next quarter. I don't think anybody believed it except the Catholics that were in the stadium.” — Chuck Bowman, Sooners guard.
Oct. 27, 1956
Oklahoma 40, Notre Dame 0
Notre Dame Stadium
The game: Oklahoma picked up its only win in the series in resounding fashion, dominating to the finish en route to a second consecutive national title. The Sooners needed just 235 yards of total offense — 147 on the ground — as the defense dominated and kept OU in good field position.
Stars: Tommy McDonald and Clendon Thomas. Each intercepted passes from eventual Heisman Trophy winner Paul Hornung and returned them for touchdowns. McDonald's 55-yard interception return put the Sooners up 26-0 at halftime. The pair also combined for 121 rushing yards.
Quotable: “It sounds great to hear half of Oklahoma cheering at Notre Dame today.” — Edith Royal, wife of former Sooners star Darrell Royal, in a telegram to the team after the win. Darrell Royal was coaching Washington at the time.
Sept. 26, 1953
Notre Dame 28, Oklahoma 21
The game: Merrill Green's second interception of the game didn't prove to be enough as Oklahoma nearly came back from a 28-14 deficit in the second half. Green had returned an interception 55 yards for a touchdown earlier in the game and picked off another late in the fourth quarter with the Sooners trailing by seven. But Notre Dame's Johnny Lattner intercepted Buddy Leake's pass to end the comeback try. Oklahoma led 14-7 early before Frank Varrichione blocked Max Boydston's punt. The Irish recovered at the Sooners 9 and scored shortly thereafter to tie the game at 14 just before half.
The Sooners tied Pittsburgh, 7-7, the next week before starting a 47-game winning streak that stretched to 1957, when OU fell to Notre Dame.
Star: Ralph Guglielmi, Notre Dame. The quarterback rushed for just three yards on 12 carries but threw for 88 yards and a pair of touchdowns to Joe Heap and rushed for another score in helping the Irish win.
Quotable: “We played good ball and have nothing to be ashamed about. Notre Dame is just a big, rough, tough team.” — Bud Wilkinson, Sooners coach.
Nov. 8, 1952
Notre Dame 27, Oklahoma 21
Notre Dame Stadium
The game: Notre Dame trailed three times after Billy Vessels gave the Sooners the lead, but the Irish came back each time. After tying it for the third time early in the fourth quarter, Notre Dame's Al Kohanovich recovered Larry Grigg's fumble on the kick return, giving the Irish the ball at the OU 24. A few plays later, Notre Dame quarterback Tom Carey gave the Irish their first lead. The Sooners had a final chance to come out with the win, but an incompletion as time ran out ended the game.
Star: Billy Vessels, Oklahoma. The Sooners came out on the losing end, but Vessels, who went on to win the Heisman Trophy, was dominant. Vessels scored all three OU touchdowns and ran for 195 yards on 17 carries. “That Vessels is one of the finest running backs I've ever seen. And I saw a lot of Vessels today,” Notre Dame coach Frank Leahy said.
Quotable: “We just threw the ball away too much.” — Eddie Crowder, Sooners quarterback.