OU, however, isn't completely out of the title hunt, thanks to losses to Florida, Rutgers and West Virginia over the weekend.
But OU will need both LSU and USC to lose once, possibly twice, to have a chance to pass them in the BCS standings.
Third-ranked California also must lose, preferably to someone other than the Trojans.
OU will also need Big Ten unbeatens Ohio State and Wisconsin to suffer losses, too.
South Florida, Boston College and Kentucky are all undefeated in BCS leagues, but chances of them staying unbeaten are unlikely.
"There's a lot that can still happen,” coach Bob Stoops said.
OU's biggest hurdle, however, might be its own schedule.
Because of Texas' tailspin, the Sooners don't appear to have any marquee games left on the schedule, which won't help them gain favor in the polls.
In fact, Texas and Missouri could be the only ranked teams left on the schedule.
So even if the Sooners run the table, a 12-1 record might not be enough to make it to New Orleans.
Then again, it just might.