EUGENE, Ore. (AP) — Early in the second quarter Washington narrowed Oregon's lead to 21-7, and Huskies coach Steve Sarkisian had hope.
But the No. 2 Ducks answered with two touchdowns and headed into halftime with a 35-7 advantage, leaving Sarkisian and the rest of the 23rd-ranked Huskies deflated.
Saturday night's game ended with a 52-21 Oregon victory.
"We really tried not to panic. We tried to stick to the plan," Sarkisian said. "We got a good drive in there to get it to 21-7 and then it got sideways on us fast."
Marcus Mariota threw for 198 yards and four touchdowns and Oregon (6-0, 3-0 Pac-12) won its ninth straight overall dating back to last season, as well as its ninth straight in the series against the rival Huskies (3-2, 1-1).
Mariota hit Colt Lyerla with touchdown passes of 10 and 13 yards. Kenjon Barner, who went into the game ranked 10th in the nation with an average of 121 yards rushing per game, ran for 122 yards.
Bishop Sankey ran for 104 yards and two touchdowns for Washington, while Keith Price threw for 145 yards and two interceptions.
"Really frustrating. We were moving the ball at times in the first half but we couldn't finish," Sankey said. "We shot ourselves in the foot too many times."
The game was the latest in the lengthy Pacific Northwest rivalry.
Huskies' fans remember "The Pick" in 1994 when freshman cornerback Kenny Wheaton saved the day for the Ducks when he intercepted a pass by Damon Huard and ran it back 97 yards for a score.
The victory sent Oregon to the Rose Bowl — and a clip is still played on the video scoreboard for fans before every home game.
The Huskies raised the ire of Ducks' fans in 2002 when, after beating Oregon 42-10, the team danced for nearly an hour on the "O'' on the 50-yard line at Autzen Stadium.
But because of Oregon's recent domination of the series, the intensity of the rivalry has diminished in recent years. The Ducks' nine-game winning streak is the longest for either side in the series history, which dates back to 1900.
There was little visible contentiousness between the two teams on Saturday night, except for a brief shoving match in the third quarter. Some of the players said there was a bit of trash talking.