DETROIT (AP) — Doug Fister and the Tigers fell so far behind, even Miguel Cabrera couldn't bring them back.
Cabrera homered and had four hits, but Detroit lost to the Boston Red Sox 10-6 on Friday night. Shane Victorino homered and hit three singles, driving in five runs for the Red Sox.
Cabrera hit a three-run homer for Detroit, which nearly rallied from a 6-1 deficit but couldn't come through against Boston's bullpen. Jon Lester (7-4) allowed five runs and nine hits in 5 2-3 innings, winning for the first time in seven starts.
The Red Sox lost Thursday night in the ninth inning, but their bullpen held the Tigers to one run Friday.
Fister (6-5) allowed six runs and 11 hits in 3 1-3 innings.
"Doug wasn't at his sharpest, but he didn't get any luck, either," Tigers manager Jim Leyland said. "I'm not making any excuses for him, but when they hit the ball hard, and they did hit some hard, they got a hit, and when they didn't hit the ball hard, they still got a hit."
Andy Dirks also homered for Detroit.
Both teams came into the game amid upheaval in the bullpen after Andrew Bailey gave up a game-winning homer to Detroit's Jhonny Peralta on Thursday. The Tigers designated Jose Valverde for assignment Friday, and the Red Sox are giving Bailey a break from closing.
Boston got through the last 3 1-3 innings Friday with Junichi Tazawa, Craig Breslow and Andrew Miller. Koji Uehara would likely have closed if the game had been tighter.
The Red Sox lead Baltimore by two games in the AL East. Cleveland trimmed Detroit's AL Central lead to three.
Fister didn't strike out a single batter, and Boston found seemingly every hole on the diamond against him. The Red Sox led 2-1 before coming up with six straight hits off Fister in the fourth. Jacoby Ellsbury's two-run double made it 4-1, and Victorino followed with a two-run single.
"Bottom line: I didn't do my job tonight," Fister said. "They're a good lineup — put the ball in play and did what they needed to do to put up runs."
It was Victorino's first four-hit game since 2011. He opened the scoring with a solo homer in the first, although the Tigers tied it in the second on Brayan Pena's RBI single.
Dustin Pedroia's run-scoring groundout in the third gave Boston a 2-1 lead, and the Red Sox scored four more the following inning.