Portland State has never beaten a team from the Pac-12 and is just 2-28 against FBS schools.
Dykes, however, has had to caution the Bears against overlooking the Vikings.
"When you have a young team like we do, every practice is important, every game is important," Dykes said. "You hope that your kids have that competitive spirit where they're going to play hard for 60 minutes every play no matter what. How we perform on Saturday will say a lot about our program and where our guys are mentally."
The Bears will go into the game without safety Avery Sebastian, who was scheduled to undergo season-ending surgery on his right Achilles tendon Thursday.
Defensive end Brennan Scarlett, who missed the opener, remains sidelined while recovering from a hand injury. Linebacker Nick Forbes (back) and nose tackle Mustafa Jalil have also been out with injuries.
"We have to do a good job of having guys step up," Dykes said. "We've lost some pretty key guys."
Portland State put up 672 yards in total offense against Eastern Oregon while running a variation of the Pistol. More than 400 yards came on the ground, as running backs D.J. Adams and Shaq Richard both went over 100 yards.
"They're very well coached in the fundamentals of the Pistol and how it's run," Dykes said. "We're going to need to get off blocks, tackle well and stay gap sound."
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