Cardinals' unbeaten season over

Kolb called the offensive effort "sickening" and said the team's lack of production set up the sacks.

"We got ourselves in a situation where they pinned their ears back and it's not ideal," Kolb said.

Arizona made a habit of winning ugly in starting the season 4-0. The Cardinals won three of the games by a combined nine points and still haven't reached 300 yards of offense in a game this season. The loss leaves Atlanta and Houston as the only unbeatens.

Second-year defensive end Robert Quinn had three of the Rams' nine sacks. St. Louis (3-2) had six total sacks in the previous four games.

Arizona coach Ken Whisenhunt said the protection needs to improve.

"We got beat on the edge a couple of times," Whisenhunt said. "We've got to work on technique and our sets, and we've got to do some things to help those guys out."

The Rams also had a strong defensive game last week in a 19-13 victory over Seattle, also at home.

Bradford busted a lengthy slump with a 52-yard touchdown pass to rookie Chris Givens for a two-TD cushion.

Lance Kendricks caught a 7-yard TD pass in the first quarter and Greg Zuerlein kicked a 53-yard field goal in the second quarter for the Rams, who are 3-0 at home and ended Arizona's seven-game winning streak in St. Louis — the Cardinals' home before leaving for the desert in 1988.

The Rams totaled two victories last year but so far have executed a quick turnaround under new coach Jeff Fisher. They're 3-0 at home for the first time since 2003, when they were unbeaten in the Edward Jones Dome and they're above .500 for the first time since they were 4-3 on Nov. 4, 2006.

Bradford had been 3 for 16 for 25 yards and an end-zone interception since the opening drive, often missing on his receivers by a lot. Undoubtedly, he missed Danny Amendola, sidelined in the second quarter with a right shoulder injury on a diving attempt that was initially ruled a 22-yard catch for a first down but overturned after the Cardinals challenged.