Okemah (26-3) also had a big performance from senior Dion Scott who finished with 14 points.
Okemah led 31-19 at halftime, but outscored Sequoyah-Tahlequah 17-5 in the third quarter to open up a 48-24 lead heading into the fourth.
Tyler Jones scored 11 points off the bench to lead Sequoyah-Tahlequah (21-8), as the Indians struggled to find open shots against Okemah's smothering defense.
“They have multiple 3-point shooters that are just unbelievable and we were able to take that away,” Simon said. “We forced them to put the ball on the floor and then we were great helping each other out defense.”