It was all Mount St. Mary (25-5) the rest of the way. The Rockets opened the final quarter on a 9-2 run that included five straight points from sophomore Adrienne Berry, who finished with 12.
The early fourth-quarter run would give Mount St. Mary the lead for good as it knocked down 7 of 8 free throws the rest of the way to seal the upset. The Rockets outscored Anadarko (27-2) by 16 points in the second half.
Junior guard Aimee Rischard added 11 points for the Rockets.
Anadarko star Lakota Beatty, an Oklahoma State signee, was limited to just nine points as she struggled to hit shots while playing with a broken index finger on her shooting hand. Senior Kelia Pachoddy led the Warriors with 12 points.
Mount St. Mary advances to play Fort Gibson for the Class 4A state championship Saturday at 7:30 p.m. at State Fair Arena.