Byng (26-4) got within four in the third quarter, but that's as close as it would ever get.
Bond finished with 24 points, 14 of which came in the second half. Jordan Hagood added 10 points, including five crucial free throws down the stretch.
Byng did not score until Breecia Crawford made a free throw with 1:56 remaining in the first quarter. The Pirates also made their first field goal with 6:30 remaining in the second on a putback by Alexis Hill, who finished with 14 points before fouling out early in the fourth.
Once she fouled out, things really went Mount St. Mary's way as it closed the game on an 8-0 run.
And as his players embraced following the victory, all Hamilton could do was smile and watch.
“I tell the girls all the time there's not many firsts in life and this is a first they're always going to remember,” he said. “It's something they can tell their kids about.”