Crawford put one last dagger in the Spurs as he dribbled down the final seconds before casually popping a deep 3 for the final basket.
"We turned the ball over way too much (22 times) and went through bad stretches. We just can't put games together like that and expect to win," Duncan said. "But it's early in the season and we're going to learn every one of these losses and continue to grow as a team. Hopefully at the end of the year, we're a better ballclub because of it."
The Clippers stretched their lead to 59-51 early in the third before the Spurs cut it to 59-58 after scoring eight straight points.
Crawford, Griffin and Paul took over the rest of the third, combining to score the Clippers' last 20 points and stretch their lead to 78-70 going into the fourth. Crawford launched the 20-12 run by hitting back-to-back 3-pointers.
The Spurs got within three points on a layup by Ginobili before Griffin scored six of the Clippers' next eight points to extend their lead.
"It's my job to keep feeding him," Paul said of Griffin. "I love it when he demands the ball. We're going to keep playing through him every night."
The Clippers trailed 28-21 after the opening quarter before unleashing a 19-0 run early in the second. Green bookended the spurt with 3-pointers, and in between five different Clippers scored to give them a 40-31 lead. Griffin scored their final eight points to send them into halftime leading 55-49.
NOTES: Crawford started for the second straight game and just the second time in 102 games with the team. ... Clippers F Stephen Jackson faced his old team for the first time since the Spurs released him last April. He was signed by the Clippers last week and had six points. ... Popovich and some of the players, including Parker, didn't arrive until about an hour before game time. "The sunset was great over Santa Monica, so we stayed a little longer," Popovich cracked.