Meanwhile, Orlando has stretches of offensive crispness both in transition and in the half-court, outscoring Denver 60-36 in the paint.
"I want to let everyone know I'm here," Davis said. "I'm here to seize the moment. I'm here to step in the gaps. It was a good night."
Injuries were a problem in the preseason with several Magic players missing part or the entire exhibition schedule with various ailments.
Turkoglu's injury means Vaughn will have to get creative to fill his slot in the starting lineup, with no true small forward healthy enough to immediately fill-in.
Rookie Maurice Harkless, who was acquired in the Howard deal, would seem to be the obvious candidate. But Vaughn said that he only recently was cleared for full-contact practice following sports hernia surgery and will need a few before he's ready for game action. He is currently day-to-day.
Afflalo, at 6-foot-5, is also an option and said he's willing to step into that role if needed.
"That's my brother from another mother, man," said point guard Jameer Nelson. "I've been with Turk so long. It's upsetting to see that. He'll be all right. He's a trooper and we'll pick him up."
Orlando led 58-37 at the break, sparked by Davis and Redick, who each had 15 first-half points.
Despite a roster dealing with several early-season injuries, Vaughn substituted liberally in the early going, playing nine different players.
The fresh legs helped the flow of the offense, with the Magic moving the ball well and getting assists on 16 of their 24 field goals for the half.
The Nuggets, who scored just 38 first-half points in their season-opener, managed only 37 in the opening 24 minutes on Friday.
Nelson said Friday's start was exactly what the Magic needed going forward.
"We're in this together," he said.
Notes: North Carolina coach Roy Williams sat courtside Friday to support Vaughn, who is the first former Williams' player to become an NBA head coach. Vaughn played for Williams in college at Kansas. ...Orlando opened the season without backup big man Gustavo Ayon (sprained left thumb), swingman DeQuan Jones (strained hip muscle) and F Al Harrington (knee). ... Karl said C Timofey Mozgov (left knee strain) ran during shoot around on Friday, and could be ready for their home opener Tuesday against Detroit...The Magic improved to 15-9 all-time in season openers.
Follow Kyle Hightower on Twitter at http://www.twitter.com/khightower.