Brett Grimes' season is over for the Atlanta Falcons. Ty Warren's career in the NFL might be over, too.
Their injuries were the most severe on the opening weekend of the season, although a neck strain suffered by Rams tackle Rodger Saffold looked worse.
Falcons cornerback Grimes tore an Achilles tendon — the team did not specify which leg — in a win at Kansas City. Grimes got the franchise tag this year when he couldn't agree on a new contract, receiving a salary of $10.2 million. The Falcons also traded for Asante Samuel to boost their secondary, but now will be without Grimes for the rest of 2012.
"Brent has made a number of big plays since we've been here," coach Mike Smith said. "He's been the cornerstone at that corner position."
Warren tore his right triceps in his first game since 2009 as Denver beat Pittsburgh. It's the same injury that sidelined him all of last season.
The 31-year-old defensive tackle missed the 2010 season, his last in New England, with a hip injury.
"Obviously we don't want to lose a player like Ty for a significant amount of time, and this obviously will be," coach John Fox said, "but we'll adjust and, 'Next man up.'"
Saffold returned to St. Louis on Monday after spending the night in Detroit. Saffold was discharged from a hospital after results of several medical tests were negative.
"We still have some further tests to do, but it appears at this point it's just a significant strain," coach Jeff Fisher said. "So he's very lucky. So that's good news on our behalf."
The bad news: St. Louis lost center Scott Wells with a broken bone in his left foot. He will need surgery and Fisher said the Rams would use the new "marquee" injured reserve rule that allows them to activate one player off IR for Week 9, and bring back Wells then.
Wells, who got a four-year, $24 million free agent deal from the Rams, has barely been on the field. He missed the first two preseason games coming off surgery on his right knee.
Bills receiver David Nelson will miss the rest of the season after tearing a ligament in his right knee, while running back Fred Jackson hurt his right knee and is out for three weeks.