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In this photo provided by the office of the mayor and posted to his Twitter account on Friday, Jan. 11, 2013, Chicago Mayor Rahm Emanuel holds a sign asking, "Any advice for people who shake a ton of hands?" The photo was tweeted during a Twitter chat held by the city's Department of Health to answer questions. To answer, Dr. Julie Morita of the health department replied via Twitter: "My advice is to wash your hands frequently and have hand sanitizer readily available!" (AP Photo/Courtesy The Mayors Office, Brooke Collins)