Blair also had eight rebounds and three assists. Jackson finished with nine points, nine rebounds and three assists.
"You know Jack, he's got the ability to do that and he played a good all-around game and it helped us stay in the lead and not lose it," Popovich said.
Jackson also pronounced Ginobili healthy, saying the guard had regained his "swag" after missing the first two games of the season with back spasms.
"I'm still trying to figure out what 'swag' means," Ginobili said. "I'm very happy of course, and that's all I care about. I feel great that I had a good game. I needed it to build confidence and hopefully I keep building from here."
Ginobili went 5 for 7 from 3-point range.
"We never covered the ball so we had to help," Denver coach George Karl said. "(The Spurs) moved the ball on the perimeter great. We have some guys that need to work a little better on defending, so we just need to need to learn how defend out there much better."
Denver finished with 21 turnovers.
NOTES: Spurs F Kawhi Leonard, hampered by quadriceps tendinitis above his left knee, missed his first game of the season. He is expected to miss at least 10 days. ... Spurs G Gary Neal missed his second game after he cut his right index finger when he picked up his luggage. Neal sported a small bandage around the index finger. ... The Spurs wore their silver alternate jersey, which features their traditional Spur logo on the front. It's the first jersey in NBA history without any writing on the front of the jersey. ... Nuggets F Wilson Chandler (hip) missed his second straight game.