"When we lose a game like that, there's nothing we can do," he said. "We battled the whole game. We lost in the ninth. Can't happen. We've got to come back tomorrow and win the next game."
Lester had a similar line over seven, allowing six hits, one run, walking one and striking out five. He entered just 2-4 with a 6.98 ERA in his last eight starts.
Lester labored in the first, throwing 32 pitches and giving up a run. Plate umpire Doug Eddings called time just as Lester was starting to throw a pitch to Chase Headley. It hit him on the foot, but was waved off. Headley then proceeded to have a 10-pitch at-bat, reaching on a single. Kyle Blanks followed with an RBI single to center.
Boston tied it 1-1 when Carp singled leading off the fourth and scored when left fielder Quentin misplayed a carom off the Green Monster on Saltalamacchia's double.
Lester settled down after the first, retiring the Padres in order on just five pitches in the second. He gave up a hit, but needed only 12 in the third.
Volquez struck out the side in the second after allowing Carp's leadoff single.
Both dugouts were warned by Eddings after Volquez hit Jose Iglesias with the first pitch in the third inning.
NOTES: Red Sox RHP Clay Buchholz, on the 15-day disabled list since June 9 with a neck strain, threw from flat ground at about 100 feet. Buchholz was 9-0 with a 1.71 ERA before the injury. ... The Padres made a lineup change about three hours before the game, moving Quentin from DH to left field and Blanks from left to DH. ... Farrell gave 1B Mike Napoli the day off and inserted Carp at first, batting him sixth. "Trying to get a few more left-handed bats in the lineup," Farrell said. ... Quentin was 0 for 11 against Lester. ... Boston SS Iglesias was named AL rookie of the month for June, the first Red Sox player to win it since Jacoby Ellsbury did it in September 2007. Iglesias hit .395 in 25 games. ... Game time temperature was 87 degrees with a steamy feeling in Fenway Park. ... The clubs conclude the three-game series Thursday afternoon with Boston rookie Allen Webster (0-2, 9.50 ERA) making his fifth major-league start against San Diego left-hander Eric Stults (6-6, 3.51 ERA).