Yukon (1-1) also had a hand in the sloppiness by refusing to go away, even when trailing by three touchdowns.
Quarterback Hayden Somerville, who threw for 330 yards and three TDs, attempted to rally a comeback.
He brought the game to the two-touchdown deficit with an 8-yard TD pass to tight end Parker Bohannan and a two-point conversion pass to Corey Sudduth with less than four minutes remaining. But Santa Fe recovered the onside kick and consumed enough time on the clock to seal the win.
Still, that left Manning expecting more out of his defense, which allowed just three points last week in a loss to Midwest City.
“We can't give up 35 points like that,” Manning said. “That's too much. We've got to be better on defense. I'm not into outscoring people and having shootouts.”
But a shootout was a better result for the Wolves, and that's in part to having Hansen back.
He connected with Malik Earl twice for TDs and Aaron Jones once.
Hansen also scored on runs of 13 and 41 yards, showing his hamstring is healthy and he's ready for the rest of the season.
“I felt good,” Hansen said. “We had a lot going on and it was good to get the jersey and be able to come here and win.”