The Huskers also surrendered Corey Brown's 76-yard punt return for a touchdown, and Bradley Roby scored on a 41-yard interception return.
Missed tackles and missed assignments cropped up, same as they did the night Nebraska allowed 653 yards in the 36-30 loss at UCLA.
"We killed ourselves," Pelini said. "We've been here before. We've done it before on the road. That's the most disappointing thing. We talk about it and talk about it and talk about. Believe me, I'm frustrated. I'm disappointed."
Halfway through the season, a defense that starts eight seniors is 92nd nationally at stopping the run (189 ypg), 73rd in scoring defense (28 ppg) and 49th in total defense (367 ypg).
The offense scored 30 points or more for the sixth straight game. But Martinez threw three interceptions and lost a fumble, the Huskers converted just five of 14 third downs, and four of seven penalties called against the offense were for false starts.
Ohio State converted three of the four turnovers into 21 points.
Running back Rex Burkhead, who ran 14 times for 119 yards, re-injured his left knee in the third quarter. Burkhead already has missed two games with a sprained ligament. Burkhead's latest injury isn't believed to be serious.
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