Despite its offensive struggles, Oklahoma State was still in the game midway through the third quarter trailing only 13-0.
But that's when Oklahoma safety Jonathan Nelson delivered a knockout blow.
Nelson picked off OSU quarterback Zac Robinson at midfield and returned the interception all the way to the Cowboy 13. Two plays later, DeMarco Murray scored from 12 yards out to put the Sooners up 20-0 and essentially put the game out of reach.
Here's what OU and OSU players had to say about Nelson's interception:
Nelson: "The key thing in football is momentum. That helped us out a lot. It got the crowd behind us, gave the offense a boost. 13-0 is still a ball game. Once you add a score to that, there may be some hanging heads on the other side."
Murray: "He's been stepping up, doing a great job for us. It was a big play."
OU receiver Ryan Broyles: "It got the fans on our side. Everything went well from there."
OSU offensive tackle Russell Okung: "They made a great play at the right time. We weren't making any plays and they did. When things like that happen, the other team is going to come out on top."
OSU defensive end Jermiah Price: "We felt the momentum shift. We tried to go out and stop them."
OU cornerback Brian Jackson: "We felt like we had some momentum going, but he snuck across the middle and picked it off and almost took it to the house. That's just a great play by a great player. It really turned us around and gave us some juice to do what we needed to do."