Joseph Randle scores 4 TDs as No. 4 Cowboys stay unbeaten

Randle had 138 yards on 14 carries and scored on runs of 16, 59 and 12 yards. He also caught a 13-yard touchdown pass in the second quarter.

Brandon Weeden had three touchdown passes after the opening snap of the second quarter. Lewis' interception and fumble recovery helped the Cowboys (7-0, 4-0 Big 12) pull away despite injuries to both starting wide receivers.

Justin Blackmon caught a touchdown pass in the first quarter before hurting his right shoulder. Hubert Anyiam was wearing a boot on his left foot in the second half.

Henry Josey had 138 yards on 25 carries and T.J. Moe had six catches for 103 yards and a score for Missouri (3-4, 1-3), which has yet to win consecutive games.

The Tigers had a strong second quarter, scoring on an 18-yard run by Kendial Lawrence and Moe's 34-yard catch from James Franklin to cut the deficit to seven, before being undone by mistakes. Franklin threw two interceptions and lost a fumble at the Oklahoma State 4, all in the second half.

Lewis intercepted a tipped pass at the Missouri 27 and three plays later Randle scored on a 16-yard run for a two-touchdown cushion midway through the third quarter.