"I don't care about that. Only thing that matters to me is that I am playing," Williams said. "It is still the same pretty much. That is why I have to cope with it. It is one of things you have to deal with."
A potentially more worrisome development is starting defensive tackle Kyle Williams being listed on the injury report as missing practice due to an ankle injury.
Without Anderson, more pressure will be placed on Mario Williams to perform up to his capabilities.
"It is going to be a huge challenge," Williams said. "Mark is a great player. Having him, his intensity, and his demeanor out on the field is definitely going to be a (challenge) for us. We have to be able to pick it up. Not just us needing to do it for ourselves, but to fill in his place and the injuries we have been faced with."
Buffalo (2-3), which plays at Arizona (4-1) on Sunday, has allowed a combined 97 points and 1,201 yards in its past two games.
NOTES: Starting C Eric Wood (foot) was limited in practice, as was starting S Jairus Byrd (chest). ... Guard Chad Rinehart, who has a calf injury, did not practice Wednesday. Left tackle Cordy Glenn and guard Kraig Urbik are both recovering from right ankle injuries. As of Wednesday, the Bills have only six offensive lineman. ... With the rash of injuries to the offensive line, the Bills signed guard Reggie Wells Wednesday. He has played in 10 NFL seasons, seven of those with Arizona. Wells is not expected to be ready for Sunday's game, but could see action the following week, when Buffalo hosts Tennessee. ... To make room for Wells, the Bills placed guard Colin Brown on injured reserve. Brown suffered a hamstring injury Sunday. ... The Bills will again practice in Tempe at Arizona State on Thursday.
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