• Celladon shares dive on failed heart drug study

    Updated: 18 hr ago

    NEW YORK (AP) — Shares of Celladon Corp. plummeted after the biotechnology company said its developing heart failure treatment failed to meet key goals in a pivotal study. The stock shed $10.18, or 74 percent, to $3.50 in premarket trading about 45 minutes before the market open. The San Diego-based company said its potential drug for heart failure, Mydicar, was no better than placebo in the study. It's a potential gene therapy, which focuses on fixing genes within a cell. The drug candidate had been given special "Breakthrough Therapy" status by the Food and Drug Administration, which allows for an expedited review.

  • Well-meaning but erroneous online medical advice can be deadly

    Updated: Sun, Apr 26, 2015

    If a heart attack doesn’t kill you, advice on your Facebook page could. An old, discredited email has found new life on social media, advising people who are alone during a heart attack to breathe deeply and cough vigorously as a way to save their lives. This supposedly increases oxygen levels and helps blood circulate. While the advice is well-intentioned, it is wrong. Dead wrong. Repeated hard coughing could turn a mild heart attack into a fatal one, said Tracy Stevens, a cardiologist at St. Luke’s Mid American Heart Institute. So-called “cough CPR” is only preferable in a hospital under expert supervision. Better advice: Immediately call 911 and chew a regular-sized aspirin.

  • She changed her life after heart attack

    Updated: Sat, Apr 25, 2015

    That December day, the day after she’d celebrated “a wonderful Christmas” with her grown children, might have been Ann Hamilton’s last. On Dec. 26, 2014, she began to feel joint pain. She nearly disregarded it; she had a pin in her left arm from an accident some years ago. “I thought it was arthritis,” she said. That night she ate Chinese takeout. “I started feeling nauseous. I thought, the Chinese food was bad.” Later, when she awoke from a sleep, she vomited. She applied a heat rub to her aching arm and then wrapped it. “Then I felt like I was being squeezed in my lower back,” she said. “I put on something very tight; I needed that squeeze to stop.” I had to sit in the bathroom beca

  • Quinn on Nutrition: Lessons on heart disease from the ancients

    Updated: Fri, Apr 24, 2015

    Ancient Egyptians ate fish, birds, barley, dates, olives, beans, onions, cucumbers and food from domesticated cattle, sheep and goats. Peruvians of old caught fish, hunted birds, deer and guinea pigs, farmed corn, potatoes and beans and raised alpaca for food and clothing. Ancestral Native American Puebloans foraged on fish, rabbit, corn, squash, nuts, acorns, deer and big horn sheep. Ancient Aleutian Islanders subsisted on fish, birds, wild berries, seals, sea otters and whales. What did these preindustrial cultures have in common? Their average age of death was around 43 years. And many of them had heart disease. We learned these facts at a presentation on a recent evening by Dr. Gregory S.

  • Autopsy: Heart failure, pepper spray killed Utah prisoner

    Updated: Wed, Apr 22, 2015

    SALT LAKE CITY (AP) — A new autopsy report shows heart failure and pepper spray both contributed to the death of a Utah prisoner who died last fall after a fight. The state medical examiner ruled the death a homicide, Utah Department of Corrections spokeswoman Brooke Adams said Wednesday.

  • $3M verdict against obstetrician

    Updated: Wed, Apr 22, 2015

    An Albuquerque jury hearing negligence claims against two Roswell physicians over the death of a mother from high blood pressure during the birth of her third child returned a $3 million verdict Tuesday against one of the physicians, obstetrician Dr. Eric Peterson. The jury found Peterson 70 percent at fault and an intensive care unit nurse, Kemischa Anderson, 30 percent at fault, while clearing Dr. Robert Rader, an internal medicine specialist, of any liability in the death of Sarahy Fierro, of Lake Arthur. Anderson was not a named defendant in the litigation, so the jury award will be reduced by the percentage of fault assigned to her. A third physician defendant, Dr.

  • ORMC Congestive Heart Failure Program

    Updated: Mon, Apr 20, 2015

    Being diagnosed with congestive heart failure (CHF) can be overwhelming, confusing and incredibly scary. You have so many questions you desperately want answers to and may not be sure where to turn. Odessa Regional Medical Center (ORMC) is here to help. ORMC now has a new health information center for patients with CHF. It is an educational program not only for the patient, but the family as well. The CHF program at ORMC provides extensive one-on-one education with a nurse who specializes in heart conditions. You will get help with understanding your diagnosis and assistance in how to manage your illness. The program also helps in teaching you how to improve your quality of life.

  • Man suffering from cardiac arrest in driveway dies

    Updated: Mon, Apr 20, 2015

    ARMUCHEE, Ga. (AP) — A Chattooga County man found in a driveway suffering from cardiac arrest has died. The Rome News-Tribune (http://bit.ly/1bd3I2V ) reports 42-year-old Nicholas Shropshire was pronounced dead Saturday evening at Redmond Regional Medical Center. Floyd County Deputy Coroner Gene Proctor says someone called an ambulance after seeing Shropshire lying in the driveway of a home in Armuchee. He says there were no vehicles nearby and no one knows how Shropshire got there. Shropshire died shortly after arriving at the hospital. Proctor says there were no visible signs of trauma. Shropshire's body has been sent to the Georgia Bureau of Investigation crime lab. ___ Information from: Rome News

  • Broomfield mom seeks big hearts to help adopted son with heart condition

    Updated: Sun, Apr 19, 2015

    Sara Wetzel can't wait for the arrival of her new son. But it could take more than nine months to meet him. Wetzel is adopting her 16-month-old son, Zhi Hui, from China. But before she can meet him, there are classes to take, mountains of paperwork and money to save. In Zhi Hui's case, there are added challenges: The chubby-cheeked baby has a heart defect that will require several costly surgeries to keep him healthy. He might even need a heart transplant as he gets older. Wetzel's heart might be big enough for the both of them, but her wallet isn't. Wetzel has launched a GoFundMe campaign to raise to $55,000 for her new son's adoption expenses and medical bills. She hopes to bring him home by February.

  • Hall of Famer Kareem Abdul-Jabbar has bypass surgery

    Updated: Fri, Apr 17, 2015

    LOS ANGELES (AP) — Basketball Hall of Famer Kareem Abdul-Jabbar was recovering Friday after undergoing quadruple coronary bypass surgery. He had the surgery a day earlier at Ronald Reagan UCLA Medical Center in Los Angeles, according to a hospital statement. Dr. Richard Shemin, who performed the surgery, said the 68-year-old former NBA and UCLA star is expected to make a full recovery. He was admitted to the hospital this week with cardiovascular disease. Abdul-Jabbar is the NBA's all-time leading scorer with 38,387 points during a 20-year career with the Los Angeles Lakers and Milwaukee Bucks that ended in 1989. The 7-foot-2 center was known for his trademark sky hook shot.

  • FDA approves Amgen heart failure drug Corlanor

    Updated: Wed, Apr 15, 2015

    Biotech company Amgen Inc. took a key step in its expansion into cardiovascular drugs Wednesday when the Food and Drug Administration approved its heart failure drug for sale in the United States. The drug called ivabradine is an oral medication that treats chronic heart failure by slowing the heart rate. Amgen will sell it under the brand name Corlanor. Amgen obtained the U.S. commercial rights for ivabradine in 2013 from French company Les Laboratoires Servier, which developed the drug and sells it in Europe. Heart failure is a condition in which the heart is weakened and unable to pump enough blood to the body. To compensate for its weakened condition, the heart often speeds up — creating additional complicat

  • BC-APFN-US-Business News Digest

    Updated: Wed, Apr 15, 2015

    Business News at 5:20 p.m. The supervisor is Dorothea Degen (800-845-8450, ext. 1680). For photos, ext. 1900. For graphics and interactives, ext. 7636. Expanded AP content can be obtained from http://www.apexchange.com. For access to AP Exchange and other technical issues, contact customersupport@ap.org or call 877-836-9477. If you have questions about transmission of financial market listings, please call 800-3AP-STOX. A selection of top photos can be found at: http://bit.ly/APTopPhotos All times EDT.

  • FDA approves new type of heart failure drug from Amgen

    Updated: Wed, Apr 15, 2015

    Patients with chronic heart failure, a deadly disease that worsens as the heart pumps less blood through the body, are getting a much-needed new option. The Food and Drug Administration has approved a novel drug from Amgen for reducing hospitalizations in some heart failure patients. Corlanor (coor'LAHN'-or) is the first medication in a dozen years for the increasingly common condition. Chronic heart kills up to half of patients within five years, despite numerous existing treatments. Rival drugmaker Novartis has another heart failure pill under review by the FDA. It could be approved this summer. Roughly 6 million Americans and 26 million people worldwide have heart failure, mostly as a chronic condition.

  • FDA panel wants heart failure risk on AstraZeneca drugs

    Updated: Tue, Apr 14, 2015

    WASHINGTON (AP) — Federal health advisers say AstraZeneca's Onglyza and a related diabetes drug should carry new information about a possible association with heart failure and death. The Food and Drug Administration's panel of diabetes experts voiced concern about data suggesting Onglyza and Kombiglyze can increase hospitalization due to heart failure and overall mortality. The panel voted 14-1 that that information should appear on the drugs' prescribing labeling. Yet the panelists also said complicating factors make it difficult to tell whether the risk is real or a statistical fluke. Considering the drug's overall benefits for treating diabetes, the panel voted 13-1, with one abstention, that the drugs' heart safety pro

  • Eight-year-old to share her survivor story at Go Red for Women Luncheon

    Updated: Tue, Apr 14, 2015

    She loves to read, play basketball, play outside and play with her dogs. At first glance, 8-year-old Marleigh Fagin seems like an average blue-eyed, blond-haired third grader. But just more than one year ago, her world changed. In 2013, Marleigh was diagnosed with a heart condition called Wolff-Parkinson White syndrome. On Thursday, Marleigh will be one of three heart survivors featured at the annual Go Red for Women Luncheon, sponsored by the American Heart Association. Marleigh was 4 years old when her family got the first clue something was wrong. “Me and my babysitter were outside on the trampoline,” Marleigh said as she sat across from an A-J Media reporter with her mother and a Bahama Bucks s

  • Texas House backs heart screenings for student athletes

    Updated: Tue, Apr 14, 2015

    AUSTIN — Student athletes in Texas would need heart screenings as part of their sports physicals under a measure the House tentatively approved Wednesday. The goal is to help prevent sudden and unexpected cardiac deaths, said the bill’s author, Rep. Wayne Smith, R-Baytown. “If we can save one kid’s life, it is worth it,” Smith said. The bill, which drew bipartisan support, would add an electrocardiogram, going into the freshman and junior years, to the physical exam required before UIL-sanctioned activity. It passed, 86-57, and requires a final procedural vote Tuesday before it heads to the Senate.

  • Scientists debate impact of removing guidelines for dietary cholesterol

    Updated: Mon, Apr 13, 2015

    Recently the annual Dietary Guidelines Advisory Committee Report stated that cholesterol was “not a nutrient of concern for overconsumption.” Some people celebrated, expecting once again to fill their bellies with unlimited amounts of butter, cheese, sausage and steak. But several notable doctors and scientists balked — and even protested. “The result has been a green light for people to eat unhealthful foods,” said Neal D. Barnard, founding president of the Physicians Committee for Responsible Medicine, in his March 24 testimony before the advisory committee. ”The committee made a scientific error on cholesterol, and to carry that mistake into the guidelines is not scientifically defensible and serves only to per

  • Arlington program aims to help congestive heart failure patients

    Updated: Sun, Apr 12, 2015

    Still weak after suffering a massive heart attack, Paula Mota learned last year that her health was worse than she thought. Doctors discovered the 58-year-old Arlington woman also had tumors throughout her body. A home visit pilot program by the Arlington fire department is helping both her spirits and her health, said her daughter, Alejandra Yokley. “She is more positive about life now,” Yokley said. “Even though she has cancer and heart problems, I think shes going to be fine now. She’s stronger now, she’s happier.” Once a week, Arlington firefighters visit her to make sure she’s taking her medication, exercising and eating healthy.

  • Polar bear at Point Defiance Zoo has cancer, heart disease

    Updated: Sun, Apr 12, 2015

    TACOMA, Wash. (AP) — Glacier, a polar bear at the Point Defiance Zoo in Tacoma, has been diagnosed with liver cancer and heart disease. The News Tribune newspaper reports (http://is.gd/Q9Hgk8 ) that veterinarians are working with specialists to craft a treatment plan for the 19-year-old polar bear. Glacier came to the zoo in 1997 after being orphaned in the wild. The health problems were initially discovered as a result of a routine Feb. 21 physical examination. The zoo said a follow-up electrocardiogram confirmed the heart issues, and an abdominal ultrasound test showed a malignant liver tumor. The zoo says that according to the Association of Zoos and Aquariums, the median life expectancy for a male polar bear in th

  • DNA analysis validates link between short stature and heart risk

    Updated: Thu, Apr 9, 2015

    When Randy Newman sang his tongue-in-cheek tune about short people, he called attention to their “little hands, little eyes” and their “little baby legs.” Nowhere does his 1978 hit mention that short people also have an increased risk of coronary artery disease. But scientists have established this link in several large studies, and a new one shows that it’s not just a coincidence. Some of the genetic variants that cause people to have short stature also tend to boost their levels of “bad” cholesterol and triglycerides — two risk factors for coronary artery disease. After examining the DNA of 65,066 people with coronary artery disease along with that of 128,383 controls, researchers calculated that the risk fo




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