At the center of “Girl Most Likely” is Wiig trying desperately to wring some truth out of all these contrivances. The “Bridesmaids” star is giving it her all, but as executive producer, Wiig shares in the blame for the shambolic, ineffective comedy surrounding her. It's hard to fathom that “Girl Most Likely” was directed by the team of Shari Springer Berman and Robert Pulcini, whose “American Splendor” told the story of misanthropic cartoonist Harvey Pekar with such style and wit. With “Girl Most Likely,” those qualities are in short supply.
— George Lang