After falling behind 15-4 at the outset, the Thunder stabilized thanks to superlative play from reserve players Kevin Martin (25 points), Derek Fisher (11) and Nick Collison (10), and eventually pulled away in the fourth quarter.
Once again, three-time scoring champ Kevin Durant led OKC's attack with 27 points, while Westbrook's replacement, Reggie Jackson, added 17 points, eight assists and seven rebounds.
The Rockets failed in their attempt to become only the fourth NBA team to force a Game 7 after trailing 3-0 and would have joined the 1951 New York Knicks (against the Rochester Royals), the 1994 Denver Nuggets (against the Utah Jazz) and the 2003 Portland Trail Blazers (against the Dallas Mavericks).
In each of those instances, the home team won Game 7 to prevent the ultimate series comeback in team sports.
Elsewhere in the NBA, history repeated itself on Friday night as for only the second time in playoff history, four Game 6s were held on the same day.
On that previous occasion, all four teams that held a 3-2 lead closed out the series, which is precisely what transpired Friday as New York, Indiana and Memphis all won their series 4-2.