Oklahoma Medical Research Foundation researcher gains lupus grant

Oklahoma researcher's studies of adult stem cells leads to possible gains in lupus knowledge.

 
By Don Mecoy | Published: October 30, 2012    Comment on this article Leave a comment

photo - Carol Webb
Carol Webb

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“We were excited to find that nearly half of the cross-section of patients we examined also over-expressed this protein compared to healthy individuals,” she said. “We don't yet know if they create too much of the protein because of the inflammatory responses that occur in lupus or if the overabundance of the protein somehow leads to the disease.”

Webb said her goal is to determine if the cells that create more of the protein are more likely to lead to auto-antibody-producing cells than the cells that express normal levels of this protein. That information could be useful in certain procedures in which doctors transplant adult stem cells to help patients create new immune cells.

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