Oklahoma Medical Research Foundation researcher says DNA packaging impacts cell division

New discovery from the Oklahoma Medical Research Foundation can help explain beginnings of birth defects.

 
BY GREG ELWELL | Published: November 6, 2012    Comment on this article Leave a comment

photo - Oklahoma Medical Research Foundation scientist Susannah Rankin.
Oklahoma Medical Research Foundation scientist Susannah Rankin.

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Imagine an architect stacking the floors of a high-rise building. If the floors shift, even slightly, elevators don't connect, pipes for water and gas lead nowhere and the building will probably fall apart.

By better understanding the basics of how chromosomes are packaged during cell division, Rankin hopes scientists will be able to find ways to predict and reduce developmental problems.

“This is really where biochemistry in human genetics and basic science converge,” she said. “It takes both research into the underpinnings of how cells work and breakthroughs in advanced genetic testing to find and develop new therapeutics.”

The research was funded by grants from the Pew Foundation and the National Center for Research Resources, a part of the National Institutes of Health.

Greg Elwell is a public affairs specialist with OMRF.

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