STILLWATER, Okla. (AP) — Case Keenum threw for 366 yards and three touchdowns, and Bryce Beall caught the go-ahead 6-yard pass off a batted ball as Houston stunned No. 5 Oklahoma State 45-35 on Saturday.
The Cougars (2-0) gave second-year coach Kevin Sumlin his first marquee win with the program's first victory over a Top 5 team since an upset of third-ranked Texas in 1984.
Oklahoma State (1-1) was coming off of perhaps the biggest opening win in the program's history last week against Georgia and vaulted into the Top 5 for the first time since 1985. But after overcoming a 17-point halftime lead, the Cowboys squandered their final chances for a win.
Zac Robinson fumbled a snap to end one OSU drive in the fourth quarter, and Jamal Robinson then returned his interception 32 yards for a score to seal the upset with 3:14 remaining.
Dez Bryant returned a punt for a touchdown against Houston for the second straight year as Oklahoma State reeled off 21 straight third-quarter points to surge ahead 28-21. But, unlike last year, Keenum and the Cougars had an answer this time.
And Oklahoma State ran out of weapons. Kendall Hunter, last year's Big 12 rushing leader, didn't play in the second half due to an apparent leg injury and Bryant also missed time. He lay sprawled out on the turf for a few moments after tipping the pass that led to Jamal Robinson's return, and trainers stretched out his right leg before he left the field.