Oklahoma State battled on the road and even led 66-60 in the closing minutes at Iowa State.
But after containing Iowa State's perimeter shooters for much of the night, the Cyclones' final four baskets were 3-pointers, including a banked-in shot at the buzzer by Scott Christopherson that lifted ISU to a 71-68 win.
The Cyclones, the Big 12's top 3-point shooting team, went 3-of-11 from long range in the first half, before making 7-of-16 after intermission.
“We just gave up too many 3s in the second half,” said Cowboys coach Travis Ford. “That was the Achilles heel for us. We did a great job guarding the 3 in the first half. Our goal was to not give up more than five.”
Still, Ford said there was much to like in the loss, especially after OSU absorbed a 106-65 beating at Baylor on Saturday.
“Everybody was wondering this week how this team would respond after (Saturday),” Ford said. “I thought they played extremely hard, executed extremely well, probably as well as we've executed all year.
“Our guys showed a lot of resilience. We really fought back from a tough game last game.”
BROWN STARTS, STARS
Since suffering a hip injury against Virginia Tech on New Year's Eve, Markel Brown hadn't appeared in Oklahoma State's starting lineup.
Brown was back in the opening five Wednesday night against Iowa State, and in a different role for much of the game, essentially taking a turn at the point. The result: 11 assists, nine points and six rebounds.
Brown's one regret was a big one — his only turnover with 4.8 seconds left, setting up the Cyclones' game-winning shot — but his overall performance offers optimism for a team struggling to create offense.