The Pacers built a 95-85 lead midway through the fourth quarter and not even the scuffle shook them up as they ended a three-game skid against Western Conference teams.
When play resumed, Ian Mahinmi made a free throw and later West had three baskets, Lance Stephenson hit a 3-pointer and George scored on a jumper to give the Pacers a 104-87 lead with 3:28 left to play.
"We knew we had to (close it out) with Roy going out," George said. "We knew we had to close that game. We're happy about this, but it's one game."
Indiana's Danny Granger played 18 ½ minutes and scored five points off the bench in his first home game this season.
He wasn't in the locker room for media availability after the game.
Pacers coach Frank Vogel said he wants to get Granger back in the starting lineup and is looking at a possible two-week timetable, but said he will review it week-by-week.
"My expectations are that we'll get him back into the starting lineup as soon as possible," Vogel said.
Curry hit a jumper and a 3-pointer and the Warriors took a 5-0 lead to start the game. Hill, who had 15 points in the first quarter, hit two 3-pointers, including one to tie the game with 4:19 left in the period.
With the Warriors trailing 52-43, Curry hit a 3-pointer and two more field goals before Lee scored on a layup to get them within 54-53 at halftime.