The atmosphere in east Jerusalem remained tense well past midnight. Hundreds of Palestinians, many of their faces covered, occupied a main road leading into Beit Hanina and the neighborhood of Shuafat. Three train stops were charred. Police continued to patrol the area. Women and children poked their heads out of windows and were repeatedly ordered by Palestinian men to stay inside.
Netanyahu called on authorities to swiftly investigate the "reprehensible murder" and urged all sides "not to take the law into their own hands."
But international condemnations came quickly.
In Washington, the Obama administration denounced the killing as a "heinous murder" and called for the perpetrators to be brought to justice.
"There are no words to convey adequately our condolences to the Palestinian people," said Secretary of State John Kerry, calling the killing "sickening."
The U.N. Security Council condemned the "heinous" killing "in the strongest terms" in a press statement, and U.N. Secretary-General Ban Ki-moon called for the perpetrators of the "despicable act" to be promptly brought to justice and a lowering of tensions.
In a statement, the European Union condemned the killing "in the strongest terms" and welcomed Israel's pledge to investigate. It urged all parties to show "maximum restraint."
Despite the calls for calm, fighting continued along Israel's southern border with Gaza.
Late Wednesday, Gaza militants fired a barrage of eight rockets toward southern Israel, for a total of 20 rockets and mortars fired on Israel throughout the day, the army said. It said anti-rocket defenses intercepted two rockets. There were no reports of casualties or damage.
The army said it carried out one airstrike on a mortar-launching site in Gaza, scoring a "direct hit." The heavy barrage late Wednesday raised the likelihood of further Israeli reprisals.
Early Thursday, a rocket fired from Gaza slammed into a house in the southern Israeli border town of Sderot, causing heavy damage to the structure and a nearby road and knocking out electricity throughout town, the army said. The family was huddled inside a shelter, and no one was hurt, the army said.
In response to the latest rocket barrage, the Israeli military said the air force carried out a "precision strike" on 15 Hamas targets in Gaza overnight Thursday, including concealed rocket launchers, weapon-storage facilities and "terror activity" sites. Ashraf al-Kidra, a Palestinian medical official, said 10 people, all civilians, including three women, suffered light to moderate wounds.
Associated Press writers Yousur Alhlou in Jerusalem, Mohammed Daraghmeh in Ramallah, West Bank, and Edith M. Lederer at the United Nations contributed to this report.