Blair repeatedly got uncontested shots at the rim off pick-and-rolls and hit a couple of nifty running bank shots, including one when Neal jumped and couldn't find anywhere to throw the ball before sliding a bounce pass to Blair just before coming back down.
"It's hard to overcome layup after layup, and that's what happened," Mavericks coach Rick Carlisle said.
When he returned early in the second quarter, Parker hit three straight shots and finished the half with 10 points. For the game, he added 10 assists and four rebounds.
The Spurs took control with a 21-6 run in the third quarter, capped by a Dallas turnover when a pass from Collison went through O.J. Mayo's legs and led to a fast break that ended with Diaw throwing a behind-the-back bounce pass to Splitter for a layup and a 74-49 San Antonio lead.
"They execute so well on offense and they make you pay and they do a good job of exploiting however your defense plays," said Vince Carter, who had 17 points for Dallas. "We just didn't adjust well enough tonight."
Dirk Nowitzki, who debuted a month ago in a 38-point loss at San Antonio after a 27-game absence following right knee surgery, had 15 points on 6-of-14 shooting. Mayo, the team's biggest 3-point threat, finished with 14 but missed all four from long range.
The Mavericks got within 10 with 4 minutes left during a strange sequence that resulted in a technical foul against Carlisle even though officials reversed the call that caused him to complain.
Vince Carter tipped in a miss, but Courtney Kirkland called goaltending. Carlisle argued and was given the technical by Eli Roe. The Spurs still got the free throw even after Carter was awarded the basket when Kirkland consulted with the crew. The Dallas deficit was briefly 10 before Neal hit the free throw and Parker drove for the back-to-back layups and a 105-90 lead.
NOTES: Budenholzer said there weren't any health problems with Ginobili, who didn't play in the second half and was scoreless on 0-of-2 shooting in just 8 minutes. "We just decided to keep him out and keep him healthy," Budenholzer said. ... Brand played in his 899th game and made his 14th start for Dallas. His last start was Dec. 6 at Phoenix.