"We just feel like this is a building we should never lose in," Pierce said. "Teams coming to the Garden, they've got to know that this is going to be their toughest game of the year. That's the feeling and the swagger that we're bringing."
Boston closed the second quarter on an 8-2 run and led 50-43 at halftime, then continued pulling away throughout the third quarter while shooting 65 percent (11 for 17).
The Celtics opened the period 7 for 9 and scored eight straight during a 12-2 run that put Boston up 70-55 on a 3-pointer by Lee. Pierce added a 3-pointer with 3:24 left, then headed to the bench with the Celtics up 75-57.
"We gave up the rim and they were able to get out in transition and also hit their 3s," Henderson said. "We settled for a lot of jump shots and we didn't get to the rim like we want to."
Boston led 83-66 after three and let the reserves open the fourth. Chris Wilcox dunked on an alley-oop and Randolph drove the baseline for a dunk, capping a 9-0 run to start the period and putting Boston ahead 92-88.
Charlotte fell behind 26-24 on Wilcox's dunk 16 seconds into the second quarter and trailed the rest of the way.
Notes: Both teams had nearly identical lines at the end of the first quarter — shooting 10 for 19, making 2 of 4 3-pointers and 2-of-2 foul shots in the 24-all tie. The Celtics had an 11-5 rebounding advantage. ... The TD Garden crew had a quick turnaround, converting the arena in time for the game to start about 3 hours, 45 minutes after the Boston Bruins beat the Washington Capitals 4-1 earlier Saturday. ... Garnett has played 63 of the team's 65 games this season, only missing a win in Phoenix when he was rested after attending the All-Star game. ... Charlotte is 6-28 on the road. ... The Bobcats have never won a season series against the Celtics. ... A photographer was knocked woozy when Charlotte's Bismack Biyombo ran into him on the baseline late in the fourth quarter.