Burnett handled Cincinnati's slumping lineup, retiring the last 10 batters he faced. Frazier hit his 19th homer off the screen on the left-field foul pole in the fourth, ending Cincinnati's streak of 16 scoreless innings.
Joey Votto singled twice, surpassing Pete Rose's club record of reaching base 311 times in a season.
NOTES: The Reds wore their Los Rojos jerseys to celebrate Hispanic Heritage Month. ... Pirates manager Clint Hurdle will change his starting pitcher on Sunday if nothing's at stake. RH Gerrit Cole (10-7) is scheduled to go against RH Johnny Cueto (5-2). Hurdle would keep Cole available as insurance for the wild-card game on Tuesday. ... Alvarez's homer gave him 99 RBIs. ... Reds manager Dusty Baker doesn't plan to use LH Tony Cingrani in relief during the series. Cingrani is recovering from his second bout of back spasms. ... Bronson Arroyo (14-11) starts on Saturday against Pittsburgh's Charlie Morton (7-4). Morton has given up only one run in his last three starts at Great American Ball Park, throwing two complete games.
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