Karain calms him down.
"She's so positive with the whole thing," Reed said. "If I hit a couple bad shots I'll start to get down on myself and she'll pick me right up immediately and won't allow me to self-sabotage my round or any hole."
Said Karain: "We make a great team. I think his attitude has improved dramatically. If he misses a putt I'm just there to say 'Hey, just let it go. Just believe in yourself — you can do it.'"
Reed said along with being his emotional support, she's also proven to be valuable in other areas, too.
"She's amazing at reading greens," he said.
It was Karain who read a 12-foot putt perfectly on the 18th hole at Zurich last Friday allowing Reed to make the cut.
"I couldn't really see the line and the next thing you know I was able to play the weekend," Reed said.
With each passing day Reed's confidence is growing.
That was evident Thursday. When playing partners Jamie Lovemark and Charlie Beljan were reaching for 3-woods, Reed was grabbing his driver.
He averaged 294 yards off the tee and needed just 26 putts.
"Just with how I've been hitting the ball, I felt like I could really attack, especially with the driver," Reed said. "I was just getting closer to the green and being able to keep it in play. I had a lot of wedges in my hands, and when I had that, I capitalized on it. Next thing you know, I'm 6 under and tied for the (early) lead."
He hopes the strong play will continue into the weekend.
The Wells Fargo Championship offers a $6.5 million purse and a chance at some economic security.
There are still 54 holes to play, but Reed would certainly love to grab a big paycheck to supplement the mere $101,813 he has earned since turning pro last summer.
"We'd definitely be taking more flights if we do well here," Reed said, laughing. "I just want to improve week to week. If I do that then I'll hopefully be able to get into the top 10. Then maybe I won't have to do these Monday qualifiers. That would be nice."