"We know he called the DREAM Act a 'handout' and that he promised to veto it," Domenzain said. "Nothing he has said since contradicts this and we should continue to take him at his word."
The Denver Post interview comes as Romney and Obama are fighting a heated battle for Colorado, whose significant Hispanic population could determine which candidate receives the state's nine electoral votes.
Throughout the Republican primary, Romney took an aggressive tack on immigration, saying in debates that he approved of "self-deportation," where undocumented workers would choose to leave the country on their own because they were unable to find work. He assailed rival Rick Perry, the Texas governor, for allowing illegal immigrants to attend Texas state colleges and universities at reduced, in-state tuition rates. Romney always has said he supports a path to citizenship for illegal immigrants who serve in the military.
After Romney secured the nomination, he indicated he would review potential legislation from Florida Sen. Marco Rubio that would allow some young illegal immigrants a way to stay in the country.
In another interview Monday with Denver television station KDVR, Romney laid out a possible scenario for paying for proposal to cut all income tax rates by 20 percent. He's previously said the cuts would be funded by closing loopholes and deductions, but that the specifics would have to be worked out with Congress.
"As an option you could say everybody's going to get up to a $17,000 deduction; and you could use your charitable deduction, your home mortgage deduction, or others — your health care deduction, and you can fill that bucket, if you will, that $17,000 bucket that way," Romney said. "And higher income people might have a lower number."
Obama spent Tuesday preparing for Wednesday's debate at a resort in Henderson, Nev., while Romney was spending most of the day in practice with plans to tour the debate stage set up on the University of Denver campus.
Associated Press writers Philip Elliott in Clinton, Iowa; Mitch Weiss in Charlotte, N.C.; and Kasie Hunt in Denver contributed to this report.