Sale's strikeout of Austin Jackson to end the third gave him 200 on the season in 190 2-3 innings pitched. It made him the fastest pitcher in White Sox history to 200 strikeouts in a season, passing Javier Vazquez in 2007 (207).
After the ejections during the top of the first, Chicago gave Sale a lead in the bottom of the inning.
The White Sox took a 2-0 advantage with two outs when Paul Konerko singled to center, driving in Alejandro De Aza and Gordon Beckham. Beckham walked with no outs and advanced to second on Adam Dunn's fly ball to center, which also got De Aza to third.
Chicago scored three times with two outs in the fourth. Dayan Viciedo's RBI single gave the White Sox a 3-0 lead, then Scherzer's throw to first on Josh Phegley's soft roller between third and home was well away from Prince Fielder, bringing in Viciedo and Jordan Danks.
Danks was in the lineup in place of former Tigers outfielder Avisail Garcia, who had two teeth pulled Monday and was held out.
Victor Martinez broke up Sale's shutout bid with one out in the seventh with his 12th home run of the season.
NOTES: White Sox general manager Rick Hahn called their season "gut-wrenching" and said they have "a number of areas we need to upgrade." ... Leyland sounded happy with the results of the July 30 three-team trade that sent Garcia to Chicago, Jake Peavy to Boston and Jose Iglesias to Detroit. Garcia entered Monday hitting .320 in 27 games for Chicago, Iglesias has replaced suspended Jhonny Peralta in the Tigers lineup and was batting .297, and Peavy was 3-1 with a 3.55 ERA, giving all three teams production from their new players. "That's what you want in trades because then you can deal with those people again," Leyland said. ... White Sox DH Adam Dunn refuted a recent report that he was considering retirement. While he did say that the White Sox playing the way they have is a "letdown" he also said "I don't know where that comes into that I'm retiring." ... White Sox pitching coach Don Cooper (diverticulitis) was back with the team after missing two games. ...Tuesday's pitching matchup is Rick Porcello (11-8, 4.76) against Chicago's Erik Johnson (0-1, 4.50).
Outpatient ROBOTIC HYSTERECTOMY. Trust an experienced Robotic Surgeon.