As many as 50 vehicles were in a pileup on I-75, between Middletown and Monroe, in southwest Ohio. A dispatcher with the State Highway Patrol said minor injuries were reported in the accident, which occurred just before noon.
State Highway Patrol Sgt. James Russell told The Middleton Journal that snow falling at the time of the pileup caused "white-out conditions" and possibly triggered the first drivers to lose control and start the crash.
Witness Luke Stevens, of Van Wert, told the newspaper he was in a vehicle at the front of the pileup.
"It was complete ice all over the highway," he said.
Four semitrailers and about 20 cars were involved in an afternoon pileup on I-71 near Mansfield, the state patrol said. And lanes of I-270 were closed temporarily following a multi-vehicle crash near Columbus.