Phoenix led by seven after the first but quickly fell into its normal second-quarter lull. Nick Young had a pair of 3-pointers and Wright added five points as the 76ers outscored the Suns 17-6 to start the period and open a 41-37 lead.
But it was Philadelphia that came out cold in the second half. Scola had consecutive baskets and Jared Dudley added a 21-foot jumper to key an 8-2 run that put the Suns ahead 56-51 with 9:38 left in the third quarter.
Lavoy Allen cut the lead to 60-59 on a 19-footer with 6:34 left in the period but the 76ers could pull no closer.
"I think tonight we turned the ball over when we didn't need to," Holliday said. "I can say I did. And the loose balls we needed to get, we didn't do that."
NOTES: Scola has scored 20 or more in three straight games. ... Phoenix has won five of its past seven at home. . The Sixers are six games into a season-high, eight-game holiday road trip. ... Phoenix beat Philadelphia for the first time since February 24, 2010. ... Dragic had a career-high three blocks, as many as the 76ers as a team. . More than 1,200 Kansas State fans, in town for Thursday's Fiesta Bowl against Oregon, were in the arena and were chanting for former Wildcat Michael Beasley to enter the game. They also booed Suns forward Markieff Morris, who played at Kansas.