Rudy Gay scored 20 points for the Kings, who concluded a five-game home stand with a 3-2 record. Both Derrick Williams and Jimmer Fredette scored 13 points.
The Kings made 15 of 30 3-pointers, shot 52 percent, and outrebounded the Cavaliers 50-32. The Kings also had eight blocks, including three by Gay.
"They shot the mess out the basketball. I give them and Mike Malone credit," Cleveland coach Mike Brown said. "From top to bottom, they kicked my behind and everybody else in a Cleveland Cavalier uniform. It wasn't just Rudy Gay and Isaiah Thomas. It was the whole ... team."
Thomas made consecutive 3s and Ben McLemore and Williams each had another in a span of two minutes, giving the Kings a 106-68 lead with 8:55 left in the fourth quarter. The lead reached a high of 46 points in the fourth quarter.
"This is very fun. Winning cures a lot of things," Thomas said. "We're playing hard right now.
Gay and Thomas both scored nine points in the third quarter when the Kings hit 12 of 13 free throws, outrebounded Cleveland 16-7 and took an 89-61 lead.
Leading by nine points at the half, the Kings expanded their lead in the third quarter. They ran off 16 unanswered points in building an 86-58 lead. Cousins and Gay started the run with consecutive three-point plays and Thomas ended the spree with a layup.
Gay and Thomas both scored 11 first-half points for the Kings, who led 59-50. Sacramento outscored the Cavaliers 29-18 in the second quarter. Miles had 11 points and Anderson Varejao 10 for Cleveland.
It was a difficult opening half for Irving. The talented Cavaliers point guard shot 1 of 7, missed both free throws, and had two points in 19 minutes.
NOTES: Miles made a contested 40-footer to end the first quarter. The 3-pointer gave Cleveland a 32-30 lead. ... Thomas hit a 3 in the fourth quarter and has now made a 3-pointer in 29 consecutive games. ... The Kings have played 22 of their first 35 games at home. They start a six-game road trip Tuesday in Indiana. ... Fredette missed his first free throw this season after connecting on his first 12. The missed free throw prevented him from completing a four-point play.