Scherzer, who led the majors with 21 wins, did not allow a hit until Shane Victorino singled to left with two outs in the sixth. Pedroia followed with an RBI double.
It was an unprecedented third consecutive playoff game in which a Tigers starter took a no-hit bid into the sixth inning. That had never been done even twice in a row before this year's Detroit staff, which boasts the AL ERA leader, the major league leader in wins and the 2011 AL Cy Young winner and MVP.
"Scherzer was terrific. He was spent," Leyland said. "Last night our bullpen was flawless, and tonight it just wasn't quite as good."
Scherzer pitched the seventh and left after throwing 108 pitches. He said his arm was tiring and he knew that would be his final inning.
The Tigers took a 1-0 lead in the second and broke it open with four runs in the top of the sixth. Miguel Cabrera hit a solo homer off Clay Buchholz and Alex Avila hit a two-run shot that gave Scherzer a 5-0 lead.
NOTES: Scherzer lost 2-1 at Fenway Park on Sept. 9 when going for his 20th win. ... Dave Roberts, whose stolen base sparked Boston's comeback in the 2004 ALCS against the New York Yankees, threw out the ceremonial first pitch. ... Ortiz's 63rd postseason game tied Jason Varitek for the Red Sox franchise record. ... Buchholz had a 1.20 ERA against the Tigers in four career starts at Fenway Park. ... Victorino's nine career hit by pitches in the postseason tie him with Alex Rodriguez for the major league record.
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