Starter Kevin Correia has just two wins in his last 11 starts and none in his past three outings. He matched his season high with five walks in five innings.
"They are an aggressive team. They don't walk a lot," he said. "I got behind some guys. It was a close game. I would throw a pitch and err on the plate more than off it. If you make a bad pitch these guys are sneaky powerful. They have a lot of home runs. There's not one guy with a ton but they a lot guys who can hit it out. "
Minnesota loaded the bases with one out in the fifth but Dan Straily worked out of it.
The Twins took a 1-0 lead on an unearned run in the third. Chris Parmelee beat out an infield single leading off the inning but shortstop Lowrie's wild throw trying to make the play sailed into the dugout as Parmelee advanced. He then beat a throw home on Alex Presley's RBI groundout.
In the sixth, Straily threw two wild pitches that allowed Arcia to go from first to second and then to third. Josh Willingham drew a two-out walk and A's manager Bob Melvin went to the bullpen. Dan Otero relieved and gave up Yosmil Pinto's tying single and walked Parmelee to load the bases.
Pedro Floriman followed with a go-ahead single against Brett Anderson.
Gardenhire remains at 997 wins as he tries to become the eighth active manager with 1,000 victories
NOTES: Minnesota third baseman Trevor Plouffe left the game with left wrist soreness. ... Arcia is tied for most extra-base hits (31) and home runs (13) by AL rookies. ... Josmil Pinto is batting .388 (19 for 49) in 14 September games.